Menopause
What We Study
Menopause is studied as a natural endocrine transition, providing a powerful biological model to investigate how sustained hormonal decline reshapes microbial ecosystems, immune function and health trajectories in women.
Rather than viewing menopause as an isolated life stage, we approach it as a systemic process in which hormonal dynamics act as ecological drivers of microbiome restructuring, contributing to immunosenescence, inflammation and increased disease susceptibility.
Our Approach
We integrate microbiome profiling with hormonal and clinical data to characterize how endocrine transitions influence microbial community structure and function. Accessible biological systems, including oral ecosystems, are used as non-invasive interfaces to capture hormone–microbiome dynamics over time.
This framework enables the identification of shared microbial patterns and functional shifts associated with hormonal aging.
Why It Matters
Understanding menopause through the lens of hormone-microbiome ecology provides insights into the mechanisms underlying healthy versus accelerated aging. This knowledge supports the development of preventive, stratification and hypothesis-driven translational strategies aimed at promoting long-term health and resilience in postmenopausal women.