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Fertility

What We Study

We investigate how hormonal dynamics shape microbial ecosystems relevant to female reproductive function. Fertility-related conditions are studied as biological contexts to understand how hormone-driven microbial restructuring influences reproductive health outcomes.

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Endometriosis-associated infertility is explored as a model system to examine how sustained hormonal imbalance affects microbiome composition and function across interconnected biological systems.

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Our Approach

Using longitudinal sampling and advanced metagenomic and metatranscriptomic analyses, we characterize how hormonal variation modulates microbial community structure and activity. Accessible microbiomes, including oral and gut ecosystems, are used as non-invasive windows into systemic hormone-microbiome interactions.

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This approach allows us to identify transferable microbial patterns and functional signatures associated with fertility-related dysfunction.

Why It Matters

Understanding fertility through the lens of hormone-microbiome ecology enables the development of non-invasive stratification frameworks and hypothesis-driven diagnostic strategies. Rather than targeting isolated conditions, this work contributes to broader principles relevant to personalized approaches in women’s reproductive health.

Dental School, University of Seville SPAIN

C. Avicena, s/n, Sevilla, SPAIN

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